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Lecture of Prof. Nurcan Buduneli, PhD

March 4, 2025

DEAR STUDENTS,

On March 11, 2025, in the Fifth Auditorium from 14.00, Prof. Nurcan Buduneli, PhD, will present lectures on „Diabetes and periodontal diseases“, „Therapeutic and prophylactic antibiotics in periodontal treatment“ and „Biomarkers for periodontal diagnosis“.

 

Annotation of the lectures:

 

Title: Therapeutic and Prophylactic Antibiotics in Periodontal Practice

The primary etiological agent for periodontal diseases is the bacteria in the dental biofilm. The bacteria and/or their toxins activate the immune system, and the host cells then cause the major part of tissue destruction seen in periodontitis. Conventional mechanical non-surgical periodontal treatment is efficient to treat the majority of periodontitis cases. Nevertheless, adjunctive treatment modalities may be required in some cases. Antibiotics are not a component of routine periodontal treatment but may be used in certain cases as adjunctive therapeutic modalities. However, the risk/benefit analysis should be performed carefully before prescribing any antibiotics. On the other hand, prophylactic antibiotics are recommended in patients with certain cardiovascular diseases/conditions.

 

Title: Diabetes and Periodontal Diseases / Treatment

Diabetes mellitus is one of the most common chronic diseases in the adult population globally and its prevalence is increasing due to changes in lifestyle, and diet in the 21st century. Diabetes affects not only the carbohydrate but also the fat and protein metabolisms and has severe consequences on the immune defense of the individual. Periodontitis is now regarded as the sixth complication of diabetes and the available evidence indicates a two-way interaction between type 2 diabetes and periodontitis. Dentists may play a significant role in the diagnosis of undiagnosed type 2 diabetes cases. A key factor for any complication of diabetes is the level of metabolic control and a close collaboration between dental care providers and general physicians is mandatory for effective preventive and therapeutic strategies.

 

Title: Biomarkers for Periodontal Diagnosis

Basic clinical periodontal evaluation includes measurement of probing depth, clinical attachment level, evaluation of the level of oral hygiene, and gingival inflammation. These clinical measurements together with radiographical investigation are routinely used for clinical periodontal diagnosis. However, the clinical periodontal parameters provide information about the past and not about the current state of periodontal disease. During the last two decades, many studies aiming to provide a reliable biomarker have been performed and published. An ideal biomarker for periodontal diagnosis should be reliable, cost-effective and preferentially applicable chair-side. At present, there are promising markers to evaluate the disease activity and treatment outcomes.