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Lecture Dr. Gresa Babochi, PhD
May 2, 2025
DEAR STUDENTS,
On May 8th, 2025, in the Fifth Auditorium from 14:00 to 15:30, Dr. Gresa Babochi, PhD from the University of Medicine, Tirana Albania will present a lecture on "DISTANT COMPLICATIONS OF ODONTOGENIC INFECTIONS" and “LESIONS OF THE ORAL CAVITY DUE TO DRUG MEDICATIONS” under Erasmus+ Program.
ABSTRACT - DISTANT COMPLICATIONS OF ODONTOGENIC INFECTIONS The term, odontogenic infection refers to an infection that originates in the tooth proper or in the tissues that closely surround it; said infection then progresses along the periodontia down to the apex, involving periapical bone and from this area, it then spreads through the bone and periosteum towards near-by or more distant structures. The relevance of this type of infection lies in that it can cause infections that compromise more distant structures via direct spread and distant spread. The conditions or factors that influence the spread of infection are dependent on the balance between patient-related conditions and microorganism-related conditions. Patient-related conditions include certain systemic factors that determine host resistance, which may be impaired in situations such as immunodeficiency syndrome or in brittle diabetes, as well as local factors that will also exert their impact on the spread of the infection. Life-threatening infections of odontogenic or upper airway origin may extend to potential spaces formed by fascial planes of the lower head and upper cervical area. Complications include airway obstruction, mediastinitis, necrotizing fascitis, cavernous sinus thrombosis, sepsis, cerebral abscess, orbital abscess, and osteomyelitis. The incidence of these “space infections” has been greatly reduced by modern antibiotic therapy. However, serious morbidity and even fatalities continue to occur.
ABSTRACT - LESIONS OF THE ORAL CAVITY DUE TO DRUG MEDICATIONS Every drug can produce untoward consequences, even when used according to standard or recommended methods of administration. In present day the number of elderly people is on the rise. This is a rapidly growing population who has chronic medical conditions and take multiple medications. Many commonly available drugs can produce untoward consequences, even when used according to standard or recommended methods of administration. Oral mucosal symptoms caused by drugs may manifest with often nonspecific symptoms, and they may mimic specific disease states such as Pemphigus vulgaris, Erythema multiforme, or Lichen planus. The lesions include ulcerations, erosions, lichenoid reactions, pigmentation, swelling, hyperplasia or more serious contitions such as erythema multiforme or Stevens Johnson’s syndrome. Many kinds of drugs cause oral ulcerations, including some β-blockers, immunosuppressants, anticholinergic bronchodilators, platelet aggregation inhibitors, vasodilators, protease inhibitors, antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), antiretrovirals, antihypertensives, drugs used in rheumatoid arthritis, etc. This presentation focuses on ulcers and/or erosions in the oral cavity induced by pharmacotherapy, their diagnosis, differential diagnosis with other lesions of the oral mucosa and the presentation of some clinical cases.